Luiz Felipe Scolari s Guangzhou Evergrande are primed for an AFC Champions League semi-final spot after securing a 3-1 victory at Kashiwa Reysol.
The 2013 champions, knocked out of last year s competition in the quarters by eventual winners Western Sydney Wanderers, took the lead after just five minutes through Daisuke Suzuki s own goal.
Scolari s compatriot Paulinho doubled the visitors advantage before the break and Gao Lin put the Chinese Super League side in full control after 58 minutes.
However, a last-gasp strike from Masato Kudo offered Kashiwa a glimpse of hope for the return leg on September 15.
In Tuesday s other quarter-final tie last season s runners-up Al Hilal prevailed 4-1 at home against Lekhwiya.